Driven by the power of the Zeno trap coupled with electron activated dissociation (EAD) fragmentation technology, this fragment-centric revolution unlocks sensitivity gains allowing you to uncover new information for certainty in your results to make better-informed decisions, faster.
Detect up to 20x more ions in every experiment and access a spectrum of tuneable fragmentation techniques to unlock new perspectives for every molecule, in every experiment.
Harness the power of Zeno SWATH data independent acquisition (DIA) to deliver a high depth of coverage, particularly on low abundance species, quickly and robustly. Routinely quantify up to twice the number of plasma proteins than previously possible and drive faster discovery of new disease markers and therapies.
Zeno trap, EAD and Zeno SWATH DIA. A high resolution mass spectrometry solution that combines MS/MS sensitivity, orthogonal fragmentation technology and a step change in SWATH DIA.
>90% ions injected into the TOF Sensitivity gains of up to 5-20X with Zeno trap pulsing Identify and quantify low abundance species
Utilize controlled electron activated dissociation (EAD)
SWATH DIA, Improved DDA and MRMHR
Dive deeper into the biomarker landscape. Zeno SWATH DIA marks a significant step-change in data independent acquisition delivering a high depth of coverage, particularly on low abundance species, quickly and robustly.
The Zeno trap in combination with SWATH Acquisition enables significant sensitivity gains through the use of Zeno trap enabling researchers to routinely quantify up to twice the number of plasma proteins than previously possible.
With sample loads as little as 10 ng and runtimes shortened to as little as 5 mins, large-scale biomarker studies can run as routine projects that are achieved in a matter of weeks, without compromising the depth of proteome coverage that can be obtained.
Zeno SWATH DIA allows the highest level of depth in your data in the shortest amount of time compared to traditional SWATH DIA.
EAD allows for a range of free electron based fragmentation mechanisms within one device. The ability to tune electron kinetic energy within an EAD experiment extend the utility of the approach to all molecules type from singly charged small molecules to large multiply charged proteins.
Ions are accumulated in the Zeno trap before being pulsed rapidly into the TOF, meaning we can detect up to 20x more ions.
Consequently, each TOF experiment contains more useful MS/MS information, particularly on lower abundance species that were previously undetectable, introducing our customers to a new sensitivity revolution.
The Zeno trap in combination with SWATH DIA a step change in DIA with significant sensitivity gains by accumulation of lesser abundant ions adding greater breadth, certainty and completeness to quantitative data at speed.
EAD technology allows you to fine tune the electron energy, accessing multiple fragmentation mechanisms that can be applied to large molecules, peptides, lipids and small molecules.
Zeno trap pulsing on demand gives the ability to detect lower abundance ions with those in abundance at the same time driving the limits of quantification achievable with accurate mass. Zeno MRM
High-throughput characterization, with rapid multi-attribute monitoring of intact biotherapeutics and identification of charge variants.
Refined source design that limit contamination for maximized uptimes.
Robustness and simplicity for high sensitivity microflow workflows.
Allows the user to switch to nanoflow regimes for the highest sensitivity.
